You may have noticed that hemorrhoid treatments such as ANUSOL^TM and ANUSOL^TM Plus come in an ointment and a suppository format. There is no difference in the medication contained in each format of the ANUSOL^TM products and it is up to your personal preference which one you use. Hemorrhoid ointments work well on both external and internal hemorrhoids, and suppositories are best for internal hemorrhoids. Always make sure you read the label and follow instructions carefully.